Natural and preformed physical factors as a component of the complex program of health and spa rehabilitation of children during the period of remission of cancer diseases (Literature review and own research results)

Summary. The relevance of the work is due to the significant prospects of a new vector of rehabilitation medicine – sanatorium rehabilitation, in particular children, in the period of remission of oncological diseases. The aim of the study – to substantiate the use of natural and preformed physical factors (magnetotherapy and "dry" carbon dioxide baths) at the sanatorium stage in a comprehensive program for the rehabilitation of children in remission of cancer diseases (CD). Materials and Methods. Bibliometric, analytical. Results. The use of a medical complex with the additional appointment of magnetotherapy (RK1) can reliably reduce the complaints of children in remission of CD with concomitant diseases of the nervous system. According to the US indicators, statistically significant positive changes in cerebral hemodynamics were established. The results of ultrasound echoEG indicate an improvement in CSF dynamics. According to EEG data, positive changes in the state of brain electrogenesis were established. After the treatment complex with the additional appointment of "dry" carbon dioxide baths (RK2), the health of the children improved. According to the indicators of ultrasound dopplerography, blood circulation in the cerebral arteries normalized in 70.0 %  of children. Venous dysgemia was recorded half as often as compared with the baseline data. Venous stasis stage ІІІ was not registered. The frequency of detection of intracranial hypertension decreased from 90.0 to 50.0 %. According to the indicators of ultrasound echoencephalography, there was an improvement in CSF dynamics in the form of a decrease in the pulsation index by half and the frequency of registration of additional echo signals by more than three times in 70.0 % of sick children. The state of electrogenesis was characterized by the normalization of the bioelectrical activity of the brain, which was accompanied by the stabilization of the functional activity of the cortex in 70.0 % of children. Conclusions. The research results indicate the effectiveness of the physical factors of magnetotherapy and "dry" carbon dioxide baths as significant components of the sanatorium-resort rehabilitation of children in the period of remission of cancer diseases

children, cancer diseases, nervous system, spa rehabilitation, magnetotherapy,

https://doi.org/10.11603/bmbr.2706-6290.2021.4.12774

[1] Karmazina  IV,  Meltseva  EM. [The  role  of  natural physical  factors  in  restoring  the  health  of  children  with oncopathology]. Proceedings of the scientific and practical conference with international participation, dedicated to the 150th anniversary of the birth of professor A.Ye. Shcherbak "Topical issues of balneology, physiotherapy and medical rehabilitation".   I.M.   Sechenov   Research Institute.2013;XXIV:191. Russian.

[2] Kents VV, Kosoverov EO, Panenko AV. [Physiotherapy and  spa  rehabilitation  of  cancer  patients.  Medical rehabilitation,  balneology,  physiotherapy].  Russ zhurn psikorer balneol reab. 2005;4:32-35. Russian.

[3] Polschakova TV. [Expediency of early rehabilitation of  children  with  oncological  diseases  under  outpatient conditions]. Med reab balneol pysiot. 2010;1: 8-11. Ukrainian.

[4] Borodulin  SD,  Galina  IV,  NerobeevVD.  Complex application of therapeutic gas "dry" carbon dioxide baths, chambers  and  physiotherapeutic  procedures:  method. recommendations. [Комплексне  застосування  лікувальних газових «сухих» вуглекислих ванн, камер та фізіотерапевтичних  процедур:  метод.  рекомендації] Odesa; 2001. Ukrainian.

[5] Adzhimamudova IV. [Dry carbon dioxide baths in the treatment  of  bronchial  asthma  in  children].Extended  abstract of candidate’s thesis. Moscow; 2002. Russian.

[6] Rau IV.[Influence of "dry" and water carbon dioxide baths on regional blood circulation and metabolic processes in patients with deforming osteoarthritis].Extended abstract of candidate’s thesis. Moscow; 1988. Russian.

[7] Persiyanova-Durnova AL. [Effect  of  carbon  dioxide baths and physical training on intracardiac hemodynamics and  remodeling  processes  in  patients  with  postinfarction cardiosclerosis with impaired left ventricular function].Extended abstract of candidate’s thesis. Moscow; 2003. Russian.

[8] Ponomarenko GN. Physical methods of treatment: a reference book. [Физические методы лечения: справочник] Saint-Petersburg: VMedA; 2002. Russian.

[9] Grushina TI. Rehabilitation in oncology: physiotherapy.[Реабилитация  в  онкологии:  физиотерапия] Moscow: GEOTAR-Media; 2006. Russian.

[10] Ulashchik  VS. [Some  results  of  the  study  of  the antitumor  effect  of  magnetic  fields  in  the  experiment]. Voprosy  kurortologii,  fizioterapii  i  lechebnoy  fizicheskoy kultury.2015;92(4): 48-53. Russian.

[11] Frantsiyants  EM,  SheikoEM.  [Antitumor  effect  of electromagnetic  fields  and  their  effect  on  pain  in  experi-mental  and  clinical  oncology].  Issledovaniya  i  praktika  v meditsine. 2019;6(2): 99-86. Russian.

[12] Plekhanov  GB.  Basic  laws  of  low-frequency electromagnetobiology.  [Основные  закономерности  низ-кочастотной  электромагнитобиологии]  Tomsk: Izdatelstvo Tomskoho Universiteta; 1990. Russian.

[13] Temuryants NA. Ultra-low-frequency electromagnetic signals  in  the  biological  world.[Сверхнизкочастотые электромагнитные сигналы в биологическом мире] Kyiv: Naukova Dumka; 1992. Ukrainian.

[14] Sakharov  DYu,  Lednitskiy  G,  Kazmin  SD.  [The reaction of tumor cells to the effect of low-frequency low-intensity EMF]. Eksp onkol. 1996;18:178-84. Russian.

[15] Ulashchik  VS. [Magnetotherapy:  modern  ideas about the mechanisms of action of magnetic fields on the body]. Zdravokhraneniye. 2015;11:21-9. Russian.

[16] Crocetti S, Beyer C, Schade G, Egli M, Frohlich J, Franco-Obregon  A.  Low  intensity  and  frequency  pulsed electromagnetic fields selectively impair breast cancer cell viability. PLoS One. 2013;8(9): e72944. DOI: 10.1371/jour-nal. pone.0072944.

[17] Shapovalova GA.[Sanatorium-and-spa rehabilitation of children in the stage of remission of oncological diseases: substantiation of differentiated programs taking into account concomitant  pathology].  Extended  abstract  of  candidate’s  thesis.  Kharkiv:  Kharkivska  medychna  akademiia pisliadyplomnoi osvity; 2021. Ukrainian.

[18] Venger O, Zhulkevych I, Mysula Yu. Psychological and  psychopathological  features  of  patients  with  skin cancer. Georgian Medical News.2021;315(6): 29-33.

[19] Krivonis TG, Zhulkevych IV. [Gender features of clinical-psychological phenomena in cancer patients]. Zdobutky klinichnoii eksperymentalnoi medytsyny. 2020;1: 115-9. DOI: 10.11603/1811-2471.2020.v.i1.11078.Ukrainian.

[20] Poberskaya VA, Shapovalova AA, Makarenko AV.[The sci entific gro und of use of physical fac tor s on the stage  of  rehabili  tatio  n  of  childr  en  who  had  oncolo  gic di  seases].  Mizhnarodnyi  zhurnal  «Reabilitatsiia  ta  pa-liatyvna  medytsyna».  2015;1(1): 37-41.  DOI  10.15574/IJRPM.2015.01.37. Russian.

[21] Polschakova  TV,  Shapovalova  GA,  Kubinina  LV, Lukash  OV.[Application  of  "dry"  carbon  dioxide  baths in  sanatorium  rehabilitation  of  children  in  the  period  of remission of oncological diseases]. Medychna reabilitatsiia, kurortolohiia, fizioterapiia. 2015;1: 29-33. Ukrainian.

[22] Shapovalova AA, Babov KD. [Dynamics of clinical and  clinical-instrumental  indices  in  children  with  accom-panying diseases of the nervous system in the period of remission of cancer with additional administration of mag-netotherapy].  Zdobutky  klinichnoi  i  eksperymentalnoi  medytsyny.  2018;2:  207-10.  DOI:  10.11603/1811-2471.2018.v0.i2.8927. Ukrainian.

[23] Shapovalova GA, Polschakova TV.[Substantiation of the method of sanatorium-resort rehabilitation of children with  oncohematological  diseases].  Ukr zhurnbiol med sport. 2018;3(5(14)):194-7. Ukrainian.

[24] Shapovalova GA. [The use of "dry" carbon dioxide baths  in  the  complex  of  rehabilitation  of  children  with concomitant  lesions  of  the  nervous  system  in  the  period of  remission  of  cancer].  Collection  of  scientific  works  of staff member of P. L. Shupyk NMAPE. 2014;23(3):375-81. Ukrainian.

[25] Shapovalova  GA,  Polschakova  TV. [Scientific substantiation of the use of "dry" carbon dioxide baths in the  rehabilitation  complex  of  children  with  concomitant pathology of the nervous system in the period of remission of  cancer]. Proceedings  of  the  International  Conference:“Topical issues of diagnosis and treatment of diseases of the nervous system”. (October 12-13Kyiv, 2017). Ukrainskyinevrolohichnyi zhurnal. 2017;3: 64. Ukrainian.

[26] Shapovalova AA. [Scientific substantiation of the use of "dry" carbon dioxide baths in the complex of rehabilitation of children with concomitant lesions of the nervous system in the period of remission of oncohematological diseases].Proceedings of the Science Conference dedicated to the Day  of  the  People's  Day  of  Mammadkarim  oglu  Aliyev (Baku, 2018).Baku; 2018. Russian.

[27] Shapovalova GA. [Magnetotherapy as a component of the complex of sanatorium rehabilitation of children with concomitant diseases of the nervous system in the period of remission of cancer]. Proceedings of the VII International Medical Сongress: Introduction of modern achievements of medical science in the practice of health care Ukraine. (April 25-27 Kyiv, 2018). Кyiv: Mizhnarodnyi medychnyi konhres; 2018. Ukrainian.

[28] Kubynina LV, Makarenko AV, Panenko AV, Poberska VO,  Polshchakova  TV,  Shapovalova  HA,  Yanchenko TS.  [Differentiated  use  of  "dry"  carbon  dioxide  baths  in sanatorium  rehabilitation  of  children  after  treatment  of oncohematological  diseases  and  malignant  neoplasms]. Кyiv; 2014. Ukrainian.

[29] Poberska VO, Shapovalova GA, Polschakova TV. [Application  of  4-chamber  "dry"  carbon  dioxide  baths  in sanatorium rehabilitation of children with oncohematological diseases].  Informatsiynyi  lystNo  267–2014.  Кyiv;  2014. Ukrainian.

[30] Pat.  Ukraine  for  utility  model  No.  88912  UA, (2006.01) А 61 Н 33/14. Poberska VO, Shapovalova GA, Polschakova TV, inventors; “Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine”. [Method of sanatorium rehabilitation of children with oncohematological diseases]. No. u 2013 10672. 2014 Apr 10, Bull. No. 7. Ukrainian.

[31] Shapovalova H, Shmakova I, Mokiienko A, Gushcha S, Plakida A. Substantiation of the additional prescription of magnetotherapy in the complex of rehabilitation of children with  concomitant  diseases  of  the  nervous  system  during remission of cancer. Balneo PRM Res J. 2021;12(1): 73-6.  Available  from:  https://repo.odmu.edu.ua:443/xmlui/handle/123456789/10058.