The impact of shift works on health of workers

A.I. Tsipkalo; Mariya I. Marushchak

Summary. Shift work, which includes extended shifts and other variable and non-standard hours, is widespread in all countries of the world. There are no statistical data on the number of employees working in shifts in Ukraine. The aim of the study – to analyze the impact of shift work on health of workers. Materials and Methods. The study looked at recent scientific publications on the Internet, including "shift work," "health," "disorders," "sleep disorders," and "quality of life." Results. A large number of studies show that shift work and night work have a negative effect on health. Such work features, for example, have been associated with cardiovascular disease, cancer, metabolic disorders, sleep disorders, gastrointestinal disorders, and reproductive and mental health disorders. Other researchers have also shown that night work or irregular changes affect sleep, drowsiness and health. The main mechanisms of adverse health effects are not fully understood, but most likely they include circadian disorders that lead to neuroendocrine and cardiometabolic stress, limited and disturbed sleep, which causes changes in immune function and cellular stress. Conclusions. An analysis of the literature on the impact of changing professions on human health has shown a negative impact on the body's systems, as well as on the quality of sleep, which leads to reduced efficiency and job satisfaction. This problem requires in-depth research to identify the main risks of this category of workers and develop methods for their prevention

[1] European Parliament and o fthe Council. Directive 2003/88/EC Concerning Certain Aspects of the Organisation of Working Time. Brussels: European Parliament. 2003.

[2] Garde AH, Harris A, Vedaa Ø, Bjorvatn B, Hansen J, Hansen AM, et al. Working hour characteristics and schedules among nurses in three Nordic countries – a compara-tive study using payroll data. BMC Nurs. 2019;18:12.

[3] Eurofound. 6th European Working Conditions Survey. 2017; Update. Luxembourg: Publications Office of the European Union.

[4] Barger LK, Ogeil RP, Drake CL, O'Brien CS, Ng KT, Rajaratnam SM. Validation of a questionnaire to screen for shift work disorder. Sleep. 2012;35(12):1693-703. DOI: 10.5665/sleep.2246. PMID: 23204612; PMCID: PMC3490362.

[5] Pepin E, Gillet P, Sauvet F. Shift work, night work and sleep disorders among pastry cookers and shopkeepers in France: a cross-sectional survey BMJ Open 2018;8:e019098. DOI: 10.1136/bmjopen-2017-019098

[6] Torquati L, Mielke GI, Brown WJ, Kolbe-Alexander T. Shift work and the risk of cardiovascular disease. A systematic review and meta-analysis including dose-response relationship. Scand. J. Work. Environ. Health. 2018;44: 229-38.

[7] Wang X, Ji A, Zhu Y, Liang Z, Wu J, Li S, Meng S, Zheng X, Xie L. A meta-analysis including dose-response relationship between night shift work and the risk of colorectal cancer. Oncotarget. 2015;22;6(28): 25046-60.

[8] Gan Y, Li LQ, Zhang LW, Yan SJ, Gao C, Hu S. Association between shift work and risk of prostate cancer: a systematic review and meta-analysis of observational stud-ies. Carcinogenesis. 2018;39: 87-97.

[9] Pahwa M, Labreche F, Demers PA. Night shift work and breast cancer risk: what do the meta-analyses tell us? Scand. J. Work Environ. Health. 2018;44: 432-5.

[10] Watanabe K, Sakuraya A, Kawakami N, Imamura K, Ando E, Asai Y, et al. Work-related psychosocial factors and metabolic syndrome onset among workers: a systematic review and meta-analysis. Obes. Rev. 2018;19: 1557-68.

[11] Gao YY, Gan T, Jiang LL, Yu L, Tang DM, Wanga YH. et al. Association between shift work and risk of type 2 diabetes mellitus: a systematic review and dose-response meta-analysis of observational studies. Chronobiol. Int. 2020;37: 29-46.

[12] Pallesen S, Bjorvatn B, Magerøy N, Saksvik IB, Waage S, Moen BE. Measures to counteract the negative effects of night work. Scand J Work Environ Health. 2010;36: 109-20.

[13] Knutsson A, Bøggild H. Gastrointestinal disor-ders among shift workers. Scand J Work Environ. Health. 2020;36: 85-95.

[14] Stocker LJ, Macklon NS, Cheong YC, BewleySJ. Influence of shift work on early reproductive outcomes a systematic review and meta-analysis. Obstet Gynecol. 2014;124: 99-110.

[15] Torquati L, Mielke GI, Brown WJ, Burton NW, Kolbe-Alexander TL. Shift work and poor mental health: a meta-analysis of longitudinal studies. Am J Public Health. 2019;109: E13-E20.

[16] Sridhar GR, Sanjana NS. Sleep, circadian dysrhythmia, obesity and diabetes. World J Diabetes.2016;7:515-22.

[17] Faraut B, Touchette E, Gamble H. Short sleep duration and increased risk of hypertension: a primary care medicine investigation. J Hypertens 2012;30:1354-63.

[18] Drake CL, Roehrs T, Richardson G, Walsh JK, Roth T. Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers. Sleep. 2004;27:1453-62.

[19] Wegrzyn LR, Tamimi RM, Rosner BA. Rotating night-shift work and the risk of breast cancer in the nurses' health studies. Am J Epidemiol 2017;186:532-40.

[20] Schernhammer ES, Laden F, Speizer FE. et al. Shift work and risk of colorectal cancer in the Nurses' Health Study. J Natl Cancer Inst. 2003;95: 825-8.

[21] Straif K, Baan R, Grosse Y. Carcinogenicity of shift-work, painting and fire-fighting. Lancet Oncol. 2007;8: 1065-6.

[22] Haus E, Smolensky M. Biological clocks and shift work: circadian dysregulation and potential long-term effects. Cancer Causes Control 2006;17:489-500.

[23] Biggi N, Consonni D, Galluzzo V, Sogliani M, Costa G. Metabolic syndrome in permanent night workers.Chronobiol Int. 2008;25:443-54.

[24] Fischer D, Lombardi DA, Folkard S, Willetts J, Christiani DC. Updating the “risk index”: a systematic review and meta-analysis of occupational injuries and work schedule characteristics. Chronobiol. Int. 2017;34: 1423-38.

[25] Folkard S. Blacktimes:Temporal determinants of transport safety. Accid Anal Prev. 1997;29:417-30.

[26] Di Muzio M, Diella G, DiSimone E, Novelli L, Alfonsi V, Scarpelli S, et al. Nurses and night shifts: poor sleep quality exacerbates psychomotor performance. Front Neurosci. 2020;14: 579938.

[27] Merkus SL, van Drongelen A, Holte KA, Labriola M, Lund T, van Mechelen W, et al. The association between shift work and sick leave: a systematic review. Occup Environ Med. 2012;69: 701-12.

[28] Mark C. Bolino, Thomas K. Kelemen, Samue lH. Matthews, Working 9‐to‐5? A review of research on nonstandard work schedules, Journal of Organizational Behavior, 2020; 42(2): 188-211.

[29] Flinkman M, Laine M, Leino-Kilpi H, Hasselhorn HM, Salantera S. Explaining young registered finnish nurses' intention to leave the profession: a questionnaire survey. Int J Nurs Stud.2008;45: 727-39.

[30] Kecklund G, Axelsson J. Health consequences of shift work and insufficient sleep. BMJ. 2016;355: i5210.

[31] Monk TH, Buysse DJ, Billy BD, Fletcher ME, Kennedy KS, Begley AE, Schlarb JE, Beach SR. Shiftworkers report worse sleep than day workers, even in retirement. J Sleep Res. 2013;22: 201-08.

[32] Boivin D, Boudreau P. Impacts of shift work on sleep and circadian rhythms. Pathologie Biologie. 2014;62: 292-301.

[33] Åkerstedt T, Perski A, Kecklund G. Sleep, stress, and burnout. In: Mh K, Roth T, Wc D, editors. Principles and practice of sleep medicine. St. Louis (Missouri): Saunders Elsevier; 2011.

[34] Törnroos M, Hakulinen C, Hintsanen M, Puttonen S, Hintsa T, Pulkki-Råback L, Jokela M, Lehtimäki T, Raita-kari OT, Keltikangas-Järvinen L. Reciprocal relationships between psychosocial work characteristics and sleep problems: A two-wave study. Work & Stress. 2017;31: 63-81.

[35] Ulhoa MA, Marqueze EC, Kanter-mann T, Skene D, Moreno C. When does stress end? Evidence of a prolonged stress reaction in shiftworking truck drivers. Chronobiol Int. 2011;28: 810-18.

[36] Gerard Kerkhof A. Shift work and sleep disorder comorbidity tend to go hand in hand, Chronobiology International. 2018;35:2: 219-28

[37] American Academy of Sleep Medicine. 2nd ed. Westchester, IL: American Academy of Sleep Medicine; 2005. The international classification of sleep disorders; diagnostic and coding manual.

[38] Drake CL, Roehrs T, Richardson G, Walsh JK, Roth T. Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers. Sleep. 2004;27(8): 1453-62.

[39] Anderson C, Sylvester L, Paik S. Recognition and diagnosis of excessive sleepiness associated with shift work disorder: results from shift workers, patients with shift work disorder and healthcare professionals participating in an internet survey. Sleep. 2011;34: A340.

[40] Anderson C, Sylvester L, Paik S. The impact of excessive sleepiness associated with shift work: results from shift workers and patients with shift work disorder participating in an internet survey. Sleep. 2100;34: A167.

[41] Gumenyuk V, Roth T, Korzyukov O. Shift work sleep disorder is associated with an attenuated brain response of sensory memory and an increased brain response to novelty: an ERP study. Sleep. 2011;33: 703-13.

[42] Saksvik I, Bjorvatn B, Hetland H, Sandal G, Pallesen S. Individual differences in tolerance to shift work – a systematic review. Sleep Med Rev. 2011;15: 221-35.

[43] Drake CL, Friedman NP, Wright KP, Jr., Roth T. Sleep reactivity and insomnia: genetic and environmental influences. Sleep. 2011;34: 1179-88.

[44] Bonnet MH, Arand DL. Situational insomnia: consistency, predictors, and outcomes. Sleep. 2003;26: 1029-36.

[45] Watson N, Goldberg J, Arquelles L, Buchwald D. Genetic and environmental influences on insomnia, daytime sleepiness, and obesity in twins. Sleep. 2006;29: 645-9.

[46] Viola A, Archer S, James L. PER3 polymorphism predicts sleep structure and waking performance. Curr Biol. 2007;17: 613-8.