Epidemiology of polycystic ovary syndrome, endometriosis and their comorbid course

  • Received 23.12.2021

  • Revised 19.01.2022

  • Accepted 23.02.2022



  • 1,109 Views

  • Retrieved from Volume 3, No. 4, 2021

  • Pages 135-145

Summary. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females. The urgency of the problem of polycystic ovary syndrome, its comorbid course, the impact on fertility, the tactics of such patients continues to grow, an increasing number of scientific papers aimed at studying this pathology The aim of the study – to analyze the literature on the prevalence of polycystic ovary syndrome, endometriosis and their comorbid course and their impact on the development of infertility. Materials and Methods. The study examined scientific publications over the past decade, as well as highly cited publications available on the Internet, the key words were "polycystic ovary syndrome", "endometriosis", "comorbidity", "infertility". Results. Infertility affects 40 % of women with PCOS. PCOS is the most common cause of anovulatory infertility. Approximately 90–95 % of women with anovulation who go to the clinic have PCOS. Endometriosis and PCOS are accompanied by changes in the functioning of the female hypothalamic-pituitary-gonadal axis, but they are still not considered as pathologies related to each other. According to scientific studies, PCOS and endometriosis are diseases that are common in women of childbearing age. Both negatively affect fertility. Brincat and co-authors reported that 10 % of the infertile population had endometriosis and PCOS, accounting for 48 % of all PCOS patients. To improve the success of ovulation induction, McGovern and colleagues discussed the importance of screening for other causes of infertility in women with PCOS, including endometriosis. Conclusions. Given the high prevalence of polycystic ovary syndrome, endometriosis, and their comorbid course, there is a need to understand the mechanisms of infertility in such patients, which will justify the tactics of treatment of infertility caused by these diseases

polycystic ovary syndrome, endometriosis, infertility, prevalence

https://doi.org/10.11603/bmbr.2706-6290.2021.4.12662

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