Analysis of fatty oil Nigella sativa l. рroduced in Ukraine and Bulgaria

  • Received 28.12.2021

  • Revised 09.03.2022

  • Accepted 29.03.2022



  • 1,378 Views

  • Retrieved from Volume 4, No. 1, 2022

  • Pages 80-83

Summary. The article presents the results of the study of the fatty acid spectrum of Nigella sativa L. seed oil grown in different geographical regions – Ukraine and Bulgaria. The task of studying the rich chemical composition of the plant due to the wide range of its pharmacological action remains relevant. The aim of the study – comparative study of the fatty acid composition of Nigella sativa L. seed oils grown in different geographical and climatic regions. Materials and Methods. Nigella sativa L. oil samples were obtained from 2 different geographically remote regions, Ukraine and Bulgaria; various producers: black seed oil (Zhestor, Ukraine) and Black seed oil (Zdravnytsia, Bulgaria).Gas chromatography was used to study the fatty acid composition of Nigella sativa L. Results. It was found that the composition of both studied samples includes 9 fatty acids: lauric, arachic, palmitic, palmitoleic, myristic, pentadecene, oleic, stearic and pentadecanoic. The content of oleic acid in the oil of the Ukrainian producer was twice as high as in the oil of the Bulgarian production. Also, the content of pentadecanoic acid in the oil of domestic sample was insignificant (0.03 %).  The percentage of the other seven fatty acids found differed slightly in the oils studied. This may indicate a slight difference in growth conditions and, as a consequence, the chemical composition of Nigella sativa L. Conclusions. The geographical and climatic region in which Nigella sativa L. is grown plays an important role in the formation of its chemical composition and this leads to changes in its pharmacological activity. However, the results obtained indicate that the difference in the relative content of fatty acids between the studied oils of Ukrainian and Bulgarian producers is insignificant

Nigella sativa L., growth conditions, fatty oil, chemical composition, pharmacological action

https://doi.org/10.11603/bmbr.2706-6290.2022.1.12831

[1] Ahmad A, Husain A, Mujeeb M, Khan SA, Najmi AK, Siddique  NA  et  al. A  review  on  therapeutic  potential  of Nigella sativa: A miracle herb. Asian Pac J Trop Biomed. 2013;3(5): 337-52.

[2] Hadi  MY,  Mohammed  GJ,  Hameed  IH. Analysis  of bioactive chemical compounds of Nigella sativa using gas chromatography-mass  spectrometry. J. Pharmacognosy Phytother. 2016;8(2): 8-24.

[3] Margout D, Kelly MT, Meunier S, Auinger D, Pelissier Y, Larroque M.  Morphological,  microscopic  and  chemical comparison  between Nigella  sativa  L.  (black  cumin)  and Nigella  damascena  L. Journal  of  Food,  Agriculture  & Environment. 2013;11(1): 165-71.

[4] Almatrafi AA. Medicinal Uses of Nigella Sativa (Black Seeds). International  Journal  of  Alternative  Medicine. 2013;21(1): 1129-31.

[5] Mamun MA, Absar N. Major nutritional compositions of black cumin seeds – cultivated in Bangladesh and the physicochemical characteristics of its oil. International Food Research Journal. 2018;25(6): 2634-9.

[6] Hussain  DSA,  Hussain  MM. Nigella  sativa (black seed) is an effective herbal remedy for every disease except death  –  a  Prophetic  statement which  modern  scientists confirm  unanimously.  Advancement  in  Medicinal  Plant Research. 2016;4(2): 27-57.

[7] El-Naggar  T,  Gómez-Serranillos  MP,  Palomino OM, Arce C, Carretero ME. Nigella sativa L. Seed extract modulates the  neurotransmitter  amino  acids  release  in cultured neurons in vitro. J Biomed Biotechnol. 2010;8.

[8] Aftab A, Asif H, Mujeeb M, Siddiqui N, Damanhouri Z,  Bhandari  A.  Physicochemical  and  phytochemical standardization with HPTLC fingerprinting of Nigella sativa L. Seeds. Pak J Pharm Sci. 2014;7(5): 1175-82.

[9] Nergiz C, Otles S. Chemical composition of Nigella sativa L. seeds. Food Chemistry. 1993;48: 259-61.

[10] Goryainov S, Khromov AV, Bakureza G, Sesar E, Ivlev AV, Vorobiev NA et al. Results of a comparative study of Nigella sativa L. Seeds oil composition. Pharmacy and Pharmacology. 2020;8(1): 29-39.