Structural analysis and etiological characteristics of oculomotor disorders in neurosurgical patients

  • Received 20.12.2021

  • Revised 28.02.2022

  • Accepted 29.03.2022



  • 848 Views

  • Retrieved from Vol. 4, No. 1, 2022

  • Pages 6-10

Summary. Oculomotor disorders (OMD) are complex multidisciplinary problem that can occur in a number of ophthalmological, neurosurgical and endocrine diseases. Da­mage to the oculomotor system can occur at various levels, from the extraocular muscles, nerves, to the nucleus, internuclear ligaments, and cortical centers. The aim of the study – to identify the etiological factors of oculomotor disorders and create a diagnostic algorithm. Materials and Methods. A survey of 400 patients with OMD of various etiologies who applied to the Neurosurgery Institute was conducted. Results. The causes of OMD in patients with neurosurgery pathology are vascular lesion in 39 %, brain tumor (35 %), severe traumatic brain injury – 18 % and inflammatory diseases (4 %). Aneurysms of various sections of internal carotid artery dominate among patients with vascular disorders. The algorithm for patients treatment with OMD and diplopia has been developed. Conclusions. It is necessary to be alert for ophthalmologists, timely diagnostics and referral to doctors of related profiles

oculomotor disorders, strabismus, diplopia, neurosurgical diseases

https://doi.org/10.11603/bmbr.2706-6290.2022.1.12965

[1] Vasileva IG, Zhdanova VN, Chopic NG, Makarova TA, Halanta ES, Tsubko OI. [Disfunction of the oculomotor (III andVI) cranial nerves associated with active herpesvirus infection]. Oftalmol Zh. 2019;1:9-17. Russian.

[2] Zhdanova VN. [Oculomotor disorders in neurosurgical patients]. Neyrokhir i neyrolog Kazahstan. 2014;2(35): 3-9. Russian.

[3] Zhadoyanni LV. [Analysis of results diagnostics and treatment patients with oculomotor disorders]. Ukr nevroloh zhurn. 2010;2(15):72-7. Ukrainian. 

[4] Nikiforov AS,  Guseva  MR.  Neuroophthalmology: a guide. [Нейроофтальмология  :  руководство] Moscow: GEOTAR-Media; 2008. Russian.

[5] Chaudhry IA,Elkhamry SM, AL-Rashed W. Carotid cavernous fistula: ophthalmological implication. Middle East Afr J Ophthalmol. 2009;16(20): 57-63. DOI: 10.4103/0974-9233.53862

[6] Chen H, Wang X, Yao Shan. The aetiologies of uni-lateral oculomotor nerve palsy:a clinical analysis on 121 patients. Somatosensory and Motor Research. 2019;36(2): 102-8. 

[7] CuiV, Kouliev T. Isolated oculomotor nerve palsy re-sulting from acute traumatic tentorial subdural hematoma Open Access Emergency Medicine. 2016;8: 97-101.

[8] Das S. Total ophthalmoplegia – a series of case reports. Delhi Journal of Ophthalmology. 2020;30: 67-71.

[9] El-Habashi N. An ocular infection model using suckling hamsters inoculated with equineherpevirus 9 (EHV-9): kinetics of the virus and time-course pathogenesis of EHV-9 induced encephalitis via the eye. Vet Pathol. 2013;50(1): 56-64.

[10] Richards BW, Jones FR, Younge BR. Causes and prognosis  in  4,278  cases of  paralysis  of  the  oculomotor, trochlear, and abducens cranial nerves. Am J Ophthalmol. 1992;113(5): 489-896.

[11] Tan A, Faroooqui S, Li X, Tan YL. Ocular manifes-tations and the clinical course of carotid cavernous sinus fistulas in Asian patients. Orbit 2014;33(1):45-51.

[12] Yokosato S, Kikkava Y, Takeda R, Kurita H. Oculo-motor nerve palsy in patient with a ruptured middle cere-bral artery aneurism. JMedInvest. 2017;64 (1,2): 165-7. DOI: 10.2152/jmi.64.165.PMID:28373616